Dental Nation
Dental technology

PRF (Platelet-Rich Fibrin)

PRF can be used alongside dental regenerative procedures to support tissue and bone formation.

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The short answer

PRF is used alongside regenerative dental procedures to support tissue and bone formation.

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PRF (Platelet-Rich Fibrin) dental educational illustration

What is PRF?

Where PRF fits in regenerative dental care
ItemRole
PRFUsed with regenerative procedures.[2][6]
Treatment aimSupport tissue and bone formation.[2][6]

[2][6]

How is PRF used in dentistry?

PRF is used as a surgical adjunct in dentistry. In periapical surgery studies, it has been used after incision, flap reflection, osteotomy, curettage and root-end resection.

[1][2][3][6][7]

What are the limits of PRF?

PRF has been used in many dental settings, but its effect in periapical surgery remains contested and needs clearer higher-level evidence.

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What the research says about PRF use
Clinical settingFinding
Periapical surgeryIts role remains contested.[2][4][5][6]
Dental proceduresInjectable PRF is a feasible regenerative adjunct.[1][2][3][6][7]

[2][4][5][6][1][3][7]

Is injectable PRF a related option?

Injectable PRF is a related form used as a regenerative adjunct to dental procedures, including work involving soft and hard tissue regeneration.

[1][2][3][6][7]

What might PRF mean after an extraction?

After tooth extraction, a systematic review found that 66.6% of included studies reported less postoperative pain with PRF, especially during the first one to three days. The same review reported better soft-tissue healing in the PRF group.

[2][4][5][6]

Does PRF prevent every problem after surgery?

No. Following impacted lower wisdom-tooth extraction, PRF reduced pain and swelling and lowered the occurrence of alveolar osteitis, but it did not prevent every postoperative complication.

[4][5][6]

Frequently asked questions

Can PRF reduce pain after a tooth extraction?

A systematic review found less postoperative pain with PRF in 66.6% of included studies, especially during the first one to three days after extraction.

[2][4][5][6]