Pain killers not helping toothache
Toothache that persists despite pain medicine can come from an inflamed nerve, infection, or a cracked tooth needing dental treatment.
The short answer
Pain medicine may dull toothache but cannot remove decay, pressure, a crack, or infection causing it. Persistent or worsening pain needs a dental examination to identify and treat the cause.

What is the direct answer?
What does this question mean?
Tooth pain comes from irritated tissues inside or around a tooth, including the pulp, periodontal ligament, gum, or bone. A cavity reaching the pulp, an abscess, a fracture, trapped food, or gum inflammation can keep stimulating those tissues after a tablet wears off.
What can you do next?
Use only the labelled dose of any pain medicine and do not combine products containing the same ingredient. Rinse gently with warm water, clean between the teeth, avoid very hot or cold foods, and arrange an examination rather than placing aspirin on the gum.
When should you seek dental care?
Seek prompt dental care if pain lasts, returns when medicine wears off, or is joined by swelling, fever, a bad taste, pain on biting, or difficulty opening the mouth. Facial or neck swelling, trouble breathing or swallowing, or rapid deterioration requires urgent medical attention.
What should you ask the dentist?
Ask whether the pulp, root, gum, or a crack is causing the pain, and what examination or dental radiograph is needed. Ask whether treatment means a filling, root canal treatment, drainage, extraction, or another option, and what to do until the appointment.
Frequently asked questions
Why does toothache return after pain medicine?
The medicine effect fades while the irritated pulp, ligament, or surrounding tissue remains affected.
Should antibiotics be used for every toothache?
No. Antibiotics do not replace removal of decay, drainage, or other dental treatment, and a dentist decides when they are appropriate.
